Gut Detox: What You Need to Know

Ready for a gut detox? Start the new year off right with Phyllanthus niruri tea or extract.

Foods contain a range of substances that can help to modulate transport, detoxify and support gut immune systems. These foods, including herbs, promote gut health and subsequently may help to prevent co-morbid diseases that are often lifestyle-related.

Gut enzymes and transporters play a critical role in nutrient transportation and food digestion. While nutrient uptake brings a range of health benefits, there’s no doubt that it may also result in undesirable effects on our bodies too. For instance, excessive intake of calories and nutrients is a health and social burden in most developed countries globally.

The epithelial wall in the intestines plays a critical role in barring exogenous/harmful compounds such as toxins and pathogenic microorganisms from entering our bodies. Clinical evidence shows that the cells in the intestinal epithelium have a detoxifying system that can act as a barrier for toxic chemicals in the gut. Detoxifying enzymes often metabolize toxic xenobiotics into less harmful substances that are then extracted by efflux.

Although the gut consists of an efficient system for nutrient uptake, pathogen elimination, and toxin expulsion, there is still a need to conduct a regular gut detox and cleanse using herbs such as Phyllanthus niruri to ensure the gut remains in good health.

More About Gut Detox

As mentioned above, the gut has a unique system for cleansing and detoxifying xenobiotic chemicals. The system comprises efflux transporters and metabolizing enzymes such as cytochrome P450 (CYPs), UDP-glucuronosyltransferase (UGT), and glutathione-S-transferase (GST). The activities of the efflux transporters and enzymes are often regulated by transcription factors such as the pregnane X receptor (PXR) and aryl hydrocarbon receptor (AhR). These transcription factors recognize xenobiotic chemicals and initiate the release of gut detox enzymes.

How Does Phyllanthus niruri Support Gut Detox?

Phyllanthus niruri is classified under the Euphorbiaceae family. Although small in size, the herb boasts of a variety of medicinal properties characterized by the bioactive ingredients present. Phyllanthus can provide gut detox support in part because it contains the following bioactive compounds:

• lignans
• phyllanthin
• hypophyllanthin
• flavonoids
• glycosinoids
• tannins

Reporter assay systems have been used to identify bioactive compounds that interact with PXR and AhR to support gut detox. These reporter assay systems show that flavonoids help in regulating the expression of efflux transporters and detoxification enzymes through interaction with transcription factors. This means that consuming Phyllanthus niruri herbal extract or looseleaf tea rich in flavonoids can support the intestinal barrier by building up the excretion and detoxification systems.

Detox Your Body with Phyllanthus Herbal Tea

The gut immune plays a fundamental role to help prevent infectious diseases that are usually caused by pathogenic viruses and bacteria. It also has an oral immunotolerance role that represses inflammatory or allergic reactions to diet. The gut immune produces IgA in the mucosa of the intestines to offer a stronger defense against infections.

Beyond gut detox support, Phyllanthus niruri offers a range of health benefits such as anti-inflammatory, immunomodulatory and antimicrobial properties. In fact, it’s our flagship product and the reason we started the company in the first place.

Phyllanthus niruri is the subject of more than 1,600 scientific studies, including this study and this study. It can go a long way toward supporting your detox and cleanse support goals by helping to protect your kidneys, your liver, and your overall digestive health. There is good reason to believe that a lifestyle-related approach to optimal health will benefit from support with Phyllanthus niruri as a health supplement.

We sell Phyllanthus niruri as an herbal tea and an herbal extract. We also sell it in small 100g (50-serving) sizes as SWISH Detox/Cleanse Support. You can learn lots more about the gut microbiome here. You can learn more about Phyllanthus niruri tea by reading our Phyllanthus FAQ.

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