A study published in The Journal of Natural Products in April 2021 reveals significant Andrographis antiviral potential.
An April 2021 study published in The Journal of Natural Products provides experimental evidence in favor of Andrographis paniculata and its major bioactive component, andrographolide, for further investigation as a possible monotherapy or in combination with other effective drugs against SARS-CoV-2 infection.
Even though the majority of infections are asymptomatic, clinical manifestations of COVID-19 vary widely, ranging from low-grade fever to severe pneumonia or death. The outcome of the infection depends largely on host factors, such as age, previous health problems, and immunological status. Acute respiratory distress syndrome, cytokine storm, and multi-organ failure are among the most critical manifestations of the disease.
Andrographis Antiviral Potential
Andrographis paniculata, known as “king of bitters”, belongs to the Acanthaceae family. Andrographis paniculata is currently used in traditional medicine to support treatment for the common cold, diarrhea, and fever due to several infectious causes and as a health tonic. A major bioactive component of Andrographis paniculata is andrographolide, a diterpene lactone in the isoprenoid family known for its broad-spectrum antiviral properties. Andrographis antiviral potential is still in the early stages of scientific analysis.
Andrographis paniculata has anti-inflammatory, antiviral, antibacterial, and antioxidant properties. Steven Buhner’s book Healing Lyme also suggests Andrographis may provide support for those suffering from Lyme disease.
Andrographis paniculata extract shows great promise as a health supplement for total body wellness, and ethnobotanical evidence suggests plant-derived natural compounds are worth investigating in order to identify potent antivirals against coronaviruses. The results of the study demonstrated that Andrographis paniculata extract and andrographolide may have a potent anti-SARS-CoV-2 activity with a high safety margin for major organs in cell culture models. As the researchers note, Andrographis antiviral properties and the safety and efficacy of andrographolide warrant further investigation in preclinical animal models and clinical studies.
To learn more about Andrographis paniculata and Andrographis antiviral potential, start with the Andrographis FAQ and review our Lyme disease resources. We also sell Andrographis paniculata extract in our online store.
Linden Botanicals sells the world’s healthiest teas and extracts, including Andrographis paniculata, Phyllanthus niruri, and Cistus incanus. These teas and extracts provide support for immune health, stress relief, energy, memory, mood, kidney health, joint health, digestive health, inflammation, hormonal balance, and detox/cleanse. Visit www.LindenBotanicals.com to shop the online store, get hundreds of valuable health tips and resources, and download the free Lessons from the Darkness e-book, which chronicles Michael Van der Linden’s four-year battle with Lyme disease.