Can Cryptolepis Eradicate B. burgdorferi? A Recent Study Says It Can.

Can Cryptolepis Eradicate B. burgdorferi - Linden Botanicals

Can Cryptolepis eradicate B. burgdorferi? A recent study says it can, thereby providing Lyme disease treatment support.


Can Cryptolepis Eradicate B. burgdorferi?

According to a 2020 study published in Frontiers in Medicine, new data shows seven herbal medicines are highly active in test tubes against Borrelia burgdorferi (B. burgdorferi), the bacteria that causes Lyme disease, compared with the control antibiotics, doxycycline and cefuroxime. Of the seven, only Cryptolepis sanguinolenta extract caused complete eradication of B. burgdorferi.

The implications of this study are far reaching, as they show that Cryptolepis sanguinolenta has the potential to improve treatment of persistent Lyme disease.

According to the study, the seven herbal medicines that have the potential ability to kill B. burgdorferi in test tubes include Cryptolepis sanguinolenta, Cistus incanus, Juglans nigra (Black walnut), Polygonum cuspidatum (Japanese knotweed), Artemisia annua (Sweet wormwood), Uncaria tomentosa (Cat’s claw), and Scutellaria baicalensis (Chinese skullcap).

In the study, only Cryptolepis sanguinolenta extract caused complete eradication of B. burgdorferi. Cryptolepis extract has traditionally been used to support treatment of malaria and the tick-borne infection Babesia. The implications of this study are far reaching, as they show that Cryptolepis sanguinolenta has the potential to improve treatment of persistent Lyme disease and suggest the need for additional laboratory and clinical studies regarding the extract’s active constituents and ability to effectively eradicate B. burgdorferi in vitro and in vivo.

The results revealed that Cryptolepis sanguinolenta extract showed strong activity against both growing B. burgdorferi and non-growing stationary phase B. burgdorferi. In subculture studies, 1% Cryptolepis sanguinolenta extract caused complete eradication, while doxycycline and cefuroxime and other active herbs could not eradicate B. burgdorferi stationary phase cells.

Lyme Disease and Chronic Illness Support

Linden Botanicals founder Michael Van der Linden battled Lyme disease for almost four years. The disease impacted every aspect of his life, including his physical and emotional health, his pocketbook, his social life, and his self-esteem. He started Linden Botanicals because the herbal teas and extracts we sell, including Cryptolepis and Cistus incanus, have the potential to help those suffering from chronic illness.

The study’s analysis of Cistus incanus also suggests that its active constituents, including carvacrol, may also have significant activity against growing and stationary phase B. burgdorferi cells. Preliminary clinical studies indicate Cistus may show antimicrobial effects against several bacteria and significant improvement in upper respiratory infection and inflammatory markers.

Primarily funded by the Bay Area Lyme Foundation, the 2020 Frontiers in Medicine study was a collaboration between researchers at the Johns Hopkins Bloomberg School of Public Health, the California Center for Functional Medicine, and FOCUS Health Group, Naturopathic.

Cryptolepis and Cistus incanus

If you’re looking for additional information about Cryptolepis sanguinolenta, Cistus incanus, Lyme disease, and B. burgdorferi, you can review our Cryptolepis FAQ, Cistus incanus FAQ, and Lyme Disease Resources.

Linden Botanicals sells Cryptolepis extract and Cistus incanus herbal tea and extract in our online store. We sell Cryptolepis as an extract. We also sell Cistus incanus as a loose-leaf herbal tea, as an extract, and as one of six herbal extracts in our ShieldsUp Immune Support Kits. The other extracts in the kit include Phyllanthus niruri, Rosa rugosa (Rose Hips), and Laricifomes officinalis (Agarikon mushroom). We created this proprietary collection to provide support for colds, flus, coughs, and invading pathogens.

Read the FAQ Lyme Resources Buy Cryptolepis


Linden Botanicals sells the world’s healthiest teas and extracts, including Cryptolepis sanguinolenta, Cistus incanus, and Phyllanthus niruri. These teas and extracts provide support for immune health, stress relief, energy, memory, mood, kidney health, joint health, digestive health, inflammation, hormonal balance, and detox/cleanse. Visit to shop the online store, get hundreds of valuable health tips and resources, and download the free Lessons from the Darkness e-book, which chronicles Michael Van der Linden’s four-year battle with Lyme disease.

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