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Cryptolepis sanguinolenta 101

Cryptolepis sanguinolenta Frequently Asked Questions

Curious about Cryptolepis sanguinolenta herbal extract? Check out these resources from our site or scroll down to find answers to common questions. If you have more questions, reach out!

Do you sell Cryptolepis sanguinolenta?

Yes! You can order it as an extract from our online store.

What other names does Cryptolepis go by?

It also goes by the names Gangamau, Nibima, Kadze, Kɔli mekari, Paran pupa, Yellow root, and Blood vine. We call it the Flowering Healer.

Why is Cryptolepis known for?

Cryptolepis benefits include supporting the immune system against a wide range of diseases, including malaria, Lyme disease, and bacterial infections.

What is its potential for Lyme disease support and Bartonella henselae support?

Cryptolepis extract has shown potential antibacterial activity against a broad spectrum of bacteria including Borrelia burgdorferi, which causes Lyme disease. In fact, it may be used as a herbal support during the treatment of tick-borne infections such as Lyme Borrelia burgdorferi and Bartonella henselae. The presence of bioactive compounds such as cryptolepine, the main alkaloid in the herb, has shown effective activity against both Gram-positive and Gram-negative bacteria. Another study reveals that the bioactive compounds may degrade DNA in Borrelia burgdorferi.

Cryptolepis may have an important supportive role in the need to develop novel treatment strategies against persister microcolonies of Borrelia burgdorferi. A 2020 study in Frontiers in Medicine involved the testing of a panel of botanical and natural products commonly used by Lyme disease patients. The scientists found Cryptolepis sanguinolenta to be highly active in vitro against both growing Borrelia burgdorferi and non-growing stationary phase Borrelia burgdorferi.

What are its cytotoxic properties?

Cryptolepis contains Indoquinoline alkaloids that exhibit strong anti-cancer properties. These alkaloids induce apoptosis and interfere with the cell cycle to prevent DNA biosynthesis. The major derivatives of indoquinoline alkaloids are neocryptolepine and cryptolepine, which are often extracted from the herb’s roots. Neocryptolepine and cryptolepine produce cytotoxic effects against several cancer cell lines including HL-60 and P388, which has the potential to hinder topoisomerase activity.

What are its cardiovascular and anti-atherosclerosis properties?

Cardiovascular conditions are among the leading causes of death globally. In 2016, more than 15.21 million people died of a stroke and heart attack.  Cryptolepis may reduce cholesterol levels by lowering low-density lipoproteins (LDL) and increasing the absorption of high-density lipoproteins. The herb may also help lower blood cholesterol and plasma lipids and inhibit platelet accumulation.

What are its anti-diabetic properties?

Type 2 diabetes, commonly referred to as diabetes mellitus, is a global concern with significant mortalities. It also results in other conditions such as nephropathy, neuropathy, retinopathy, and macrovascular disorders. The World Health Organization predicts that the number of diabetic patients will rise to 300 million by 2025. Cryptolepis sanguinolenta contains bioactive compounds that produce potent anti-diabetic activities (e.g., insulin secretagogue activity, removing insulin from the pancreas, and increasing plasma insulin concentration). The herb has proven to be able to multi-target and has shown to be effective in helping to control diabetes.

What are its anti-inflammatory activities?

Cryptolepis has been used traditionally to treat several inflammatory diseases. Some of the more common inflammatory diseases include osteoarthritis and rheumatoid arthritis. Cryptolepine produces nitric oxide that may act against inflammatory agents.

What anti-malarial support does it provide?

For years, malaria has remained a global pandemic with an estimated 3.3 billion people at risk globally. While several antimalarial drugs have helped in achieving the 90% malarial eradication rate, hundreds of thousands of deaths are still being reported around the world.

Cryptolepis sanguinolenta has proved to contain anti-parasitic activities against Plasmodium falciparum, a parasite that causes malaria. Cryptolepine exhibits high gametocytocidal properties that contribute to the herb’s potent antimalarial activity. The alkaloids interfere with the parasite’s lifecycle at both the asexual and sexual stages. Scientists suggest that a combination of amodiaquine and cryptolepine could be an effective combination to help achieve a 100% malaria eradication rate.

What are Persister Desister Lyme Disease Support Kits?

Persister Desister is a proprietary collection of herbal extracts is designed to:

  • Provide adaptogenic immune support
  • Inhibit the lifecycle of persister bacteria
  • Re-engage the body’s natural defenses
  • Support kidney and liver health
  • Protect against free radical damage
  • Support mitochondrial health

Each Persister Desister Kit contains individual packets of three key immune health support supplements:

  • Cryptolepis sanguinolenta (Yellow Root)
  • Cistus incanus (Rock Rose)
  • Phyllanthus niruri (Chanca Piedra)

You can learn more here.

What phytochemicals are in Cryptolepis?

Cryptolepis sanguinolenta contains several bioactive compounds that contribute to the herb’s medicinal value. Some of these bioactive compounds include:

  • Tannins
  • Flavones
  • Alkaloids
  • Polyuronides
  • Anthocyanosides
  • Chloroform

What are the plant’s traditional uses?

A tea made from Cryptolepis sanguinolenta has traditionally been used to support the treatment of malaria for many years. Research reveals that anti-plasmodial components are found in the herb’s roots, leaves, and stems. These anti-plasmodial components are commonly known as indoquinoline alkaloids. The herbal tea preparation is free of caffeine and preservatives.

How do I consume Cryptolepis extract?

Instructions: Add 1/4 teaspoon of concentrate to 8 ounces of water or a cup of juice. Stir until dissolved. Drink 1-2 glasses a day.

How did you choose your Cryptolepis supplier?

For each of the products we sell, company owner Michael Van der Linden and members of our team do substantial research, visit the source, and meet with the collectors and processors personally. We back up our faith in our source and our processors with testing.

Why should I buy Cryptolepis from Linden Botanicals?

Cryptolepis is also known as Yellow Root. It’s an all-natural herbal supplement that has antimicrobial, antioxidant, anti-inflammatory, hypotensive, and renal vasodilatory properties. It can help to balance metabolic function.

This herb is a powerhouse. But it’s not an easy herb to properly extract.

What should you look for in a Cryptolepis herbal supplement? We get this question a lot. The main active ingredients in Cryptolepis sanguinolenta are alkaloids and triterpenes. The most active alkaloid is cryptolepine. Other important alkaloids include cryptoheptine and cryptoquindoline.

The thing to know is that these bioactives have distinctive colors.

Cryptolepine, when extracted, is a dark purple powder. Cryptoheptine is a reddish brown. Cryptoquindoline is light yellow. The bright yellow of the root comes from an anthocyanoside and is sometimes used as a textile dye.

When selecting Cryptolepis for its optimal health benefits, the best extract will be yellowish-brown in color.

All-natural Cryptolepis herbal extract should be yellowish-brown instead of bright yellow due to its natural composition and the extraction process. The yellowish-brown color indicates that the extract contains the full spectrum of active compounds from the plant, including alkaloids like neocryptolepine and other beneficial constituents. A bright yellow color might suggest that the extract has been overly processed or that artificial colors have been added, which could mean it lacks some of the natural, health-promoting properties of a less refined, more authentic product.

Linden Botanicals uses a dual-stream method to provide a full spectrum extraction of Cryptolepis (Yellow Root). We believe it is the best extraction method available for those looking to optimize its benefits while also optimizing their health.

Does Cryptolepis contain caffeine?


What if I have more questions about Cryptolepis?

Contact us!

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